# Adaptation - Therapy elicits adaptation - Measurable increase in immunologically active resource - Null sides - Consensus on sufficient quantitative increase ## No Specification - No agreement on desired adaptation - Redundant, as voluntarism - # Modification - Interferon type 1 response - Circulatory IgG against HU1 - Effect on future unknown pathogens - Cross reactivity (previous and going forward) - Affect T-cell responses against other pathogens - The health of the relations in a system isn't to be determined by your choice of metrics. The relations are so complex and deeply embedded that the only hope of addressing the widest range of them for the longest term is organically, and that simply can't be expected through force.