## Adverse Reactions https://pubmed.ncbi.nlm.nih.gov/20349363/ Estimates 4.8 - 83 per 100k (top rounding 1 / 1000) Posits 1/500k-1000k allergic reaction Anaphylaxis 1 / 1500k "Reactions limited to injection site" due to aluminium salt or microbial component ## Under Reporting https://pubmed.ncbi.nlm.nih.gov/28166783/ Studied 49 GPs 209 / 100k (6 times higher than reported to State) 50% in 5 year old after booster dose Local-events/fever 2nd day after administration, lasting 4 days Indicates health care providers do not always report ## Unknown Adaptation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394856/ We are aware that viruses can substitute amino acids with the materials in which they are propogated/cultured. This issues affect virus receptor-binding. ### Rare adverse events https://tp.amegroups.com/article/view/26465/27269 ### mRNA vaccines 10-fold higher rate of anaphylaxis https://pubmed.ncbi.nlm.nih.gov/33580823/