So why have any other about vaccines at all? what is it that anyone might be afraid of? why would anyone not something which enhances their safety, functionality/capabilities, viability, vitality, lifespan, longevity, health and wellbeing? and i think the issue here is that we must make assumptions about many of these things will it enhance my safety? well I suppose it depends on the vaccine in the case of something which is almost no risk at all atleast in sofar that it might result in mortality it becomes difficult because I need to presuppose that a) the variant of he virus is relevant to that which I would be protected against from having taken the vaccine b) if I were to incur any symptoms of from having taken the vaccine, they themselves would be less pronounced and less significant than the symptoms which would accompany an actual infection by the targeted pathogen c) there are no symptoms manifesting from components of the vaccine which are not the virus itself; OR there are no symptoms manifesting that are qualitatively different from those that would manifest from the virus, or its analog, in whatever form happens to be present in the vaccine d) there are no other unwanted or detrimental effects that might be incurred, whether noticed or not one of the biggest issues that I have is the presumption that the antibody counts themselves (seroprevalence) should be the focus / primary factor by which to measure efficacy it becomes very complicated to measure efficacy because you need to have some measurable material factor, such as seroprevalance you need to compute the estimated number of cases of infection by that pathogen for a given time frame then estimate the given number of cases that would have occurred without immunization and make an assertion as to the efficacy of hte vaccine on having prevented those theoretical infections we need to consider that the manner by which the cases is reported is consistent with other pathogens/diseases, and not limited to this specific pathogen exit