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The U.K. is expected to dominate Europe in terms of market share and market revenue and will continue to flourish its dominance during the forecast period. CBD oils work by disrupting the activity of pain receptors in your body and causes a release of hormones (dopamine and serotonin) which will make you "feel good". Linalool is monoterpene alcohol, which has a relaxing effect on the body. To date, the effect of CBD on enteric gliosis which occurs during acute and chronic gut inflammation has not yet been evaluated. Therefore, the present study aims to evaluate: (a) the effect of CBD on enteroglial-derived S100B protein expression in a mouse model of acute intestinal inflammation and in rectal biopsies derived from patients with ulcerative colitis