Consensus on sufficient quantitative increase
No agreement on desired adaptation
Interferon type 1 response
Circulatory IgG against HU1
Effect on future unknown pathogens
Cross reactivity (previous and going forward)
The health of the relations in a system isn't to be determined by your choice of metrics. The relations are so complex and deeply embedded that the only hope of addressing the widest range of them for the longest term is organically, and that simply can't be expected through force.